Category: Research Highlight

Halloysite-Polymer Composites for Controlled Antibiotic Release

By: Sean M. Bittner, Lee Robeson, Edward W. Davis Effective wound treatment is a prominent issue in medicine. Identifying and treating persistent infections is particularly important, as untreated infections can rapidly escalate. Halloysite, a naturally abundant, nontoxic clay nanotube, can be loaded with 10-30 wt % antibiotic, extending release from minutes to hours or days, and…Continue Reading Halloysite-Polymer Composites for Controlled Antibiotic Release

Expanding the Scope of Gallium-Catalyzed Olefin Epoxidation

By: Fraser Bronston, Christian R. Goldsmith Catalysts that allow common synthetic reactions to take place in water instead of the usual organic solvents have long been sought after because of their potential to offset both the cost and the environmental impact of research and industry. The majority of catalysts used in modern synthetic chemistry fall…Continue Reading Expanding the Scope of Gallium-Catalyzed Olefin Epoxidation

Study of Dissociative Electron Attachment to Carbon Tetrafluoride (CF4) Using the Momentum Imaging Method

By: James Edmond, Dylan Reedy, Allen Landers, Michael Fogle Dissociative electron attachment (DEA) is a type of atomic-level process in which a low-energy (sub-ionization energy) electron attaches to a molecule, forming an anion. This molecular anion species is transitory and leads to bond relaxation. As the bond relaxes, it can eject the additional electron and return…Continue Reading Study of Dissociative Electron Attachment to Carbon Tetrafluoride (CF4) Using the Momentum Imaging Method

Exploring the Scope of a New Cascade Reaction

By: Taylor Farmer, Peter Livant, Xiaoxun Li A central challenge to synthetic organic chemists is forming a bond between two carbon atoms. The ability to form carbon-carbon bonds allows one to join together, with precise control, two smaller molecules to form a larger, more complex product. This is a core activity of the synthetic organic…Continue Reading Exploring the Scope of a New Cascade Reaction

The Effects of Macronutrients on Inducing Satiety via Peptide YY

By: Caroline E. Hubbard, Heidi A. Kluess, Leslie E. Neidert, Elise K. Mann Several metabolic polypeptides are present in the saliva. These include peptide YY (PYY), which is a known substrate of the enzyme dipeptidyl-peptidase IV (DPP-IV). DPP-IV cleaves PYY into PYY3-36, a form that can bind to the Y2 receptor in the mouth that is…Continue Reading The Effects of Macronutrients on Inducing Satiety via Peptide YY

A Cross Correlation-Based Stock Forecasting Model

By: Sungil Kim, Michael E. Baginski Researchers are continuously seeking to develop and improve stock forecasting models by analyzing the past value of a company and predicting future performance based on past data trends. Prior literature on stock analysis focuses heavily on forecasting a single stock price based on its own past data. This type…Continue Reading A Cross Correlation-Based Stock Forecasting Model

Variations of Toeplitz’ Conjecture

By: Doyon Kim, Andras Bezdek In 1911, Otto Toeplitz conjectured the following: Every Jordan curve in the plane contains all four vertices of a square. In mathematics, a curve is called Jordan curve if it is planar (can be drawn on a paper), simple (does not cross itself) and closed (walking along the curve starting at…Continue Reading Variations of Toeplitz’ Conjecture

Development and Application of Gold-lipidic Nanocomposites to Enhance Chemotherapeutic Delivery and Release

By: Christina M. Pickering, Connor S. Dobson, Peter R. Panizzi, Allan E. David, Robert D. Arnold Liposomal drug carriers are nano-scale, spherical particles with a phospholipid bilayer surrounding an aqueous core and are commonly used for chemotherapeutic delivery. Chemotherapy efficacy is limited by toxicity and tumor drug resistance; however, with increased circulation and improved tumor…Continue Reading Development and Application of Gold-lipidic Nanocomposites to Enhance Chemotherapeutic Delivery and Release

Regioselective Functionalization of [n]para-terphenylophanes

By: Natasha Narayanan, Bradley L. Merner [n]para-terphenylophanes are compounds that contain three benzene rings linked at the para, or most remote, positions (Figure 1). The two outer (terminal) benzene rings are connected by a “tether” consisting of a bridge of atoms, where [n] refers to the number of atoms in the tether. Due to this tether…Continue Reading Regioselective Functionalization of [n]para-terphenylophanes